AI Inference · x402 · early usage

Change stream for PDUFA dates a company put in an SEC filing: every set, extension and…

by api.biotechcatalystsentinel.com · discovered, not yet claimed by its owner · updated 2026-10-12

30d calls3

30d payers2

MethodGET

Outputjson

Mirrored from Coinbase's public x402 Bazaar. The description is the provider's own text and has not been reviewed here; the payment requirements are copied as published.

What it does

Change stream for PDUFA dates a company put in an SEC filing: every set, extension and resolution of every tracked catalyst, with the outcome (approval or CRL), the filing quote and its EDGAR source, as a since-cursor feed. Use when you mirror those disclosed dates and need changes as they land, not a snapshot. Accuracy and coverage are free at GET /v1/accuracy. Flat price per request.

Tags: bazaar

Call contract

Method: GET
Input: query parameters
Output: json
Last paid call: 2026-10-12

Input example from Bazaar metadata

{
  "limit": 100,
  "since": 0
}

Output example

{
  "data": [
    {
      "accession": "0009999001-25-000090",
      "application_number": "BLA999901",
      "applied": true,
      "attestation_uid": "0x1111111111111111111111111111111111111111111111111111111111111111",
      "authority": "llm_high",
      "catalyst_id": 990001,
      "company": "Sample Therapeutics, Inc.",
      "confidence": "high",
      "date_changed": true,
      "date_confidence": "confirmed",
      "days_to_date": null,
      "delta_days": null,
      "detected_at": "2025-11-03T13:41:09.000000+00:00",
      "drug_name": "SAMPLIMAB",
      "event_id": 990101,
      "event_type": "new_date_assigned",
      "filed_at": "2025-11-03",
      "indication": "sample indication (moderate-to-severe examplitis)",
      "merged_into": null,
      "new_date": "2026-04-18",
      "new_date_upcoming": false,
      "outcome": null,
      "prior_date": null,
      "source_quote": "The FDA has assigned a PDUFA target action date of April 18, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
      "source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900125000090/0009999001-25-000090-index.htm",
      "ticker": "XSMPL",
      "tickers": [
        "XSMPL",
        "XPRTN"
      ]
    }
  ],
  "meta": {
    "has_more": false,
    "limit": 100,
    "next_since": 990106,
    "total": 1
  }
}

Use with an agent

Discover. Agents find this listing with GET https://bazaar.saylorinnovations.com/discovery/search?query=…, the MCP tool search_resources, or /discovery/resources.
Inspect. Fetch /resources/31299.json for the price and payment options.
Pay. Call GET https://api.biotechcatalystsentinel.com/v1/events. The provider answers 402 with its payment requirements. An x402 client signs one of the options below and retries with PAYMENT-SIGNATURE.
Execute. The provider returns 200 with the data. Agent Bazaar is not in the request path and never sees your payment.

For humans

You don't need an account or an API key; you need a wallet holding a small amount of USDC on Base, Solana, and an x402-capable client (see the examples below). Call the endpoint unpaid first to see exactly what it asks for.

Pricing & payment

Price: $0.05 / request
Protocol: x402 v2
Auth: No account or API key. Pay per request.
Networks: Base, Solana
Demand: 3 calls · 2 unique payers in 30d (public x402 Bazaar data)

x402 payment requirements

Scheme	Network	Asset	Amount	Pay to	Timeout
exact	Base eip155:8453	USDC	$0.05	0xcD8975137D48ED9bfD1C299a62c01420B860070d	300s
exact	Solana solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp	USDC	$0.05	3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM	300s

accepts[] (raw JSON)

[
  {
    "scheme": "exact",
    "network": "eip155:8453",
    "payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "50000",
    "amountUsd": 0.05,
    "maxTimeoutSeconds": 300
  },
  {
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "amount": "50000",
    "amountUsd": 0.05,
    "maxTimeoutSeconds": 300
  }
]

Schemas

Output schema (JSON Schema)

{
  "properties": {
    "example": {
      "properties": {
        "data": {
          "description": "One row per state change, oldest-first while draining a `since` cursor. `tickers` lists every co-filer exposed to the decision.",
          "items": {
            "properties": {
              "accession": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "application_number": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "applied": {
                "type": "boolean"
              },
              "attestation_uid": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "authority": {
                "enum": [
                  "human_lock",
                  "llm_high",
                  "regex",
                  "llm_medium",
                  "llm_low",
                  null
                ],
                "type": [
                  "string",
                  "null"
                ]
              },
              "catalyst_id": {
                "type": "integer"
              },
              "company": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "confidence": {
                "enum": [
                  "high",
                  "medium",
                  "low",
                  null
                ],
                "type": [
                  "string",
                  "null"
                ]
              },
              "date_changed": {
                "type": "boolean"
              },
              "date_confidence": {
                "enum": [
                  "confirmed",
                  "reported",
                  "estimated",
                  null
                ],
                "type": [
                  "string",
                  "null"
                ]
              },
              "days_to_date": {
                "type": [
                  "integer",
                  "null"
                ]
              },
              "delta_days": {
                "type": [
                  "integer",
                  "null"
                ]
              },
              "detected_at": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "drug_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "event_id": {
                "type": "integer"
              },
              "event_type": {
                "enum": [
                  "new_date_assigned",
                  "date_extension",
                  "decision_outcome",
                  "retracted",
                  "restored",
                  "corrected"
                ],
                "type": "string"
              },
              "filed_at": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "indication": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "merged_into": {
                "type": [
                  "integer",
                  "null"
                ]
              },
              "new_date": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "new_date_upcoming": {
                "type": "boolean"
              },
              "outcome": {
                "enum": [
                  "approved",
                  "tentative",
                  "crl",
                  "none_found",
                  null
                ],
                "type": [
                  "string",
                  "null"
                ]
              },
              "prior_date": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "source_quote": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "source_url": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "ticker": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "tickers": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              }
            },
            "required": [
              "event_id",
              "catalyst_id",
              "event_type"
            ],
            "type": "object"
          },
          "type": "array"
        },
        "meta": {
          "description": "Result metadata, e.g. total count.",
          "type": "object"
        }
      },
      "type": "object"
    },
    "type": {
      "type": "string"
    }
  },
  "required": [
    "type"
  ],
  "type": "object"
}

Example shape — generated from the schema, not a captured live response

{
  "example": {
    "data": [
      {
        "accession": "string",
        "application_number": "string",
        "applied": true,
        "attestation_uid": "string",
        "authority": "human_lock",
        "catalyst_id": 0,
        "company": "string",
        "confidence": "high",
        "date_changed": true,
        "date_confidence": "confirmed",
        "days_to_date": 0,
        "delta_days": 0,
        "detected_at": "string",
        "drug_name": "string",
        "event_id": 0,
        "event_type": "new_date_assigned",
        "filed_at": "string",
        "indication": "string",
        "merged_into": 0,
        "new_date": "string",
        "new_date_upcoming": true,
        "outcome": "approved",
        "prior_date": "string",
        "source_quote": "string",
        "source_url": "string",
        "ticker": "string",
        "tickers": [
          "string"
        ]
      }
    ],
    "meta": {}
  },
  "type": "string"
}

Examples

curl

curl -X GET 'https://api.biotechcatalystsentinel.com/v1/events'
# -> 402 Payment Required; read PAYMENT-REQUIRED
# retry the identical request with PAYMENT-SIGNATURE

JavaScript

const res = await fetch("https://api.biotechcatalystsentinel.com/v1/events", {
  "method": "GET"
});
if (res.status === 402) {
  const { accepts } = await res.json();
  // pay one of accepts[] via an x402 client, then retry with the payment header
}

Python

import httpx
res = httpx.request("GET", "https://api.biotechcatalystsentinel.com/v1/events")
if res.status_code == 402:
    accepts = res.json()["accepts"]
    # pay one of accepts[] via an x402 client, then retry with the payment header

Details

Provider: api.biotechcatalystsentinel.com
Endpoint: https://api.biotechcatalystsentinel.com/v1/events
Machine-readable: /resources/31299.json