{
  "x402Version": 2,
  "id": 3592,
  "slug": "3592",
  "resource": "https://api.biotechcatalystsentinel.com/v1/events",
  "description": "FDA drug-approval catalyst change stream for US-listed biotechs: every state change of every tracked catalyst — each PDUFA date as set, extended and resolved — with the real outcome (approval or CRL), the SEC filing quote and its EDGAR source, as a since-cursor delta feed. Use when you mirror the calendar and need date changes and outcomes as they land, not a snapshot. Accuracy AND coverage are free at GET /v1/accuracy. Flat price per request.",
  "type": "http",
  "accepts": [
    {
      "scheme": "exact",
      "network": "eip155:8453",
      "payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
      "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
      "amount": "50000",
      "maxTimeoutSeconds": 300
    },
    {
      "scheme": "exact",
      "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
      "payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
      "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
      "amount": "50000",
      "maxTimeoutSeconds": 300
    }
  ],
  "outputSchema": {
    "bazaar": {
      "info": {
        "input": {
          "method": "GET",
          "queryParams": {
            "limit": 100,
            "since": 0
          },
          "type": "http"
        },
        "output": {
          "example": {
            "data": [
              {
                "accession": "0009999001-25-000090",
                "application_number": "BLA999901",
                "applied": true,
                "authority": "llm_high",
                "catalyst_id": 990001,
                "company": "Sample Therapeutics, Inc.",
                "confidence": "high",
                "date_changed": true,
                "date_confidence": "confirmed",
                "days_to_date": null,
                "delta_days": null,
                "detected_at": "2025-11-03T13:41:09.000000+00:00",
                "drug_name": "SAMPLIMAB",
                "event_id": 990101,
                "event_type": "new_date_assigned",
                "filed_at": "2025-11-03",
                "indication": "sample indication (moderate-to-severe examplitis)",
                "merged_into": null,
                "new_date": "2026-04-18",
                "new_date_upcoming": false,
                "outcome": null,
                "prior_date": null,
                "source_quote": "The FDA has assigned a PDUFA target action date of April 18, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
                "source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900125000090/0009999001-25-000090-index.htm",
                "ticker": "XSMPL",
                "tickers": [
                  "XSMPL",
                  "XPRTN"
                ]
              }
            ],
            "meta": {
              "has_more": false,
              "limit": 100,
              "next_since": 990106,
              "total": 1
            }
          },
          "type": "json"
        }
      },
      "schema": {
        "$schema": "https://json-schema.org/draft/2020-12/schema",
        "properties": {
          "input": {
            "additionalProperties": false,
            "properties": {
              "method": {
                "enum": [
                  "GET",
                  "HEAD",
                  "DELETE"
                ],
                "type": "string"
              },
              "queryParams": {
                "properties": {
                  "limit": {
                    "default": 100,
                    "description": "Maximum number of events to return (1-500; default 100).",
                    "maximum": 500,
                    "minimum": 1,
                    "type": "integer"
                  },
                  "since": {
                    "description": "Cursor: return only events with an event_id greater than this (0 = from the start). Pass the last event_id you saw to page forward.",
                    "minimum": 0,
                    "type": "integer"
                  },
                  "ticker": {
                    "description": "Optional server-side filter: only events whose record is filed by this ticker's issuer or exposes it as a co-filer in tickers[] (case-insensitive). Composes with since — limit counts matched events, so a filtered backlog drains without gaps. Unknown ticker returns an empty 200. Does not change the price.",
                    "maxLength": 12,
                    "minLength": 1,
                    "pattern": "^\\S+$",
                    "type": "string"
                  }
                },
                "required": [],
                "type": "object"
              },
              "type": {
                "const": "http",
                "type": "string"
              }
            },
            "required": [
              "type",
              "method"
            ],
            "type": "object"
          },
          "output": {
            "properties": {
              "example": {
                "properties": {
                  "data": {
                    "description": "One row per state change, oldest-first while draining a `since` cursor. `tickers` lists every co-filer exposed to the decision.",
                    "items": {
                      "properties": {
                        "accession": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "application_number": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "applied": {
                          "type": "boolean"
                        },
                        "authority": {
                          "enum": [
                            "human_lock",
                            "llm_high",
                            "regex",
                            "llm_medium",
                            "llm_low",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "catalyst_id": {
                          "type": "integer"
                        },
                        "company": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "confidence": {
                          "enum": [
                            "high",
                            "medium",
                            "low",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "date_changed": {
                          "type": "boolean"
                        },
                        "date_confidence": {
                          "enum": [
                            "confirmed",
                            "reported",
                            "estimated",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "days_to_date": {
                          "type": [
                            "integer",
                            "null"
                          ]
                        },
                        "delta_days": {
                          "type": [
                            "integer",
                            "null"
                          ]
                        },
                        "detected_at": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "drug_name": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "event_id": {
                          "type": "integer"
                        },
                        "event_type": {
                          "enum": [
                            "new_date_assigned",
                            "date_extension",
                            "decision_outcome",
                            "retracted",
                            "restored",
                            "corrected"
                          ],
                          "type": "string"
                        },
                        "filed_at": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "indication": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "merged_into": {
                          "type": [
                            "integer",
                            "null"
                          ]
                        },
                        "new_date": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "new_date_upcoming": {
                          "type": "boolean"
                        },
                        "outcome": {
                          "enum": [
                            "approved",
                            "tentative",
                            "crl",
                            "none_found",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "prior_date": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "source_quote": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "source_url": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "ticker": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "tickers": {
                          "items": {
                            "type": "string"
                          },
                          "type": "array"
                        }
                      },
                      "required": [
                        "event_id",
                        "catalyst_id",
                        "event_type"
                      ],
                      "type": "object"
                    },
                    "type": "array"
                  },
                  "meta": {
                    "description": "Result metadata, e.g. total count.",
                    "type": "object"
                  }
                },
                "type": "object"
              },
              "type": {
                "type": "string"
              }
            },
            "required": [
              "type"
            ],
            "type": "object"
          }
        },
        "required": [
          "input"
        ],
        "type": "object"
      }
    }
  },
  "tags": [
    "bazaar"
  ],
  "sourceHost": "api.biotechcatalystsentinel.com",
  "lastUpdated": "2026-09-06T10:06:03.908Z",
  "quality": {
    "calls30d": 12,
    "uniquePayers30d": 1,
    "lastCalledAt": "2026-09-06T10:06:03.327Z"
  },
  "liveness": {},
  "verified": false,
  "featured": false,
  "provider": {
    "host": "api.biotechcatalystsentinel.com",
    "manifest_name": "api.biotechcatalystsentinel.com",
    "source": "cdp-mirror",
    "source_manifest_url": "https://api.cdp.coinbase.com/platform/v2/x402/discovery/resources",
    "submitted_at": "2026-09-18T22:00:31.484Z"
  }
}