{ "x402Version": 2, "id": 38926, "slug": "38926", "resource": "https://api.magentlab.com/api/calc/reach_b", "description": "Yang 2011 REACH-B 17-point HCC risk (non-cirrhotic REVEAL-HBV). Sex female 0, male 2; age 30-65 (30-34 0 through 60-65 6); ALT U/L <15 0, 15-44 1, >=45 2; HBeAg positive 2; HBV DNA copies/mL <10000 0, 10000-99999 3, 100000-999999 5, >=1000000 4. Returns score 0-17 and published 3/5/10-year percents. Not a diagnosis, not a biopsy, not for cirrhosis. magent does not assay ALT or HBV DNA.", "type": "http", "serviceName": "magent", "resourceType": "Agent Service", "accepts": [ { "scheme": "exact", "network": "eip155:8453", "payTo": "0x836Be278f1739fB4308091cD1852F7971Bc19Ee2", "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913", "amount": "5000", "amountUsd": 0.005, "maxTimeoutSeconds": 600 } ], "outputSchema": { "properties": { "example": { "type": "object" }, "type": { "type": "string" } }, "required": [ "type" ], "type": "object" }, "extensions": { "bazaar": { "info": { "iconUrl": "https://api.magentlab.com/favicon.ico", "input": { "body": { "items": [ { "age": 30, "alt_u_l": 14, "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "sex": "female" }, { "age": 30, "alt_u_l": 14, "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "sex": "female" } ] }, "method": "POST", "type": "http" }, "output": { "example": { "count": 2, "items": [ { "age_years": 30, "alt_u_l": 14, "citation": { "authors": "Yang HI, Yuen MF, Chan HL, et al", "doi": "10.1016/S1470-2045(11)70077-8", "id": "yang-2011", "pmid": "21497551", "source": "Lancet Oncol. 2011;12(6):568-574", "title": "Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score" }, "components": [ { "factor": "sex", "points": 0, "present": false, "value": "female" }, { "factor": "age", "points": 0, "present": false, "value": 30 }, { "factor": "alt", "points": 0, "present": false, "value": 14 }, { "factor": "hbeag", "points": 0, "present": false }, { "factor": "hbv_dna", "points": 0, "present": false, "value": 200 } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "formula": "reach_b", "formula_expression": "REACH-B = sex + age + ALT + HBeAg + HBV DNA copies/mL; female 0, male 2; age 30-34 -> 0, 35-39 -> 1, 40-44 -> 2, 45-49 -> 3, 50-54 -> 4, 55-59 -> 5, 60-65 -> 6; ALT <15 -> 0, 15-44 -> 1, >=45 -> 2; HBeAg positive 2; HBV DNA copies/mL <300 -> 0, 300-9999 -> 0, 10000-99999 -> 3, 100000-999999 -> 5, >=1000000 -> 4; max 17; 3/5/10-year HCC percent from Yang 2011 score table", "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "max_score": 17, "risk_10y_percent": 0, "risk_3y_percent": 0, "risk_5y_percent": 0, "score": 0, "sex": "female" }, { "age_years": 30, "alt_u_l": 14, "citation": { "authors": "Yang HI, Yuen MF, Chan HL, et al", "doi": "10.1016/S1470-2045(11)70077-8", "id": "yang-2011", "pmid": "21497551", "source": "Lancet Oncol. 2011;12(6):568-574", "title": "Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score" }, "components": [ { "factor": "sex", "points": 0, "present": false, "value": "female" }, { "factor": "age", "points": 0, "present": false, "value": 30 }, { "factor": "alt", "points": 0, "present": false, "value": 14 }, { "factor": "hbeag", "points": 0, "present": false }, { "factor": "hbv_dna", "points": 0, "present": false, "value": 200 } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "formula": "reach_b", "formula_expression": "REACH-B = sex + age + ALT + HBeAg + HBV DNA copies/mL; female 0, male 2; age 30-34 -> 0, 35-39 -> 1, 40-44 -> 2, 45-49 -> 3, 50-54 -> 4, 55-59 -> 5, 60-65 -> 6; ALT <15 -> 0, 15-44 -> 1, >=45 -> 2; HBeAg positive 2; HBV DNA copies/mL <300 -> 0, 300-9999 -> 0, 10000-99999 -> 3, 100000-999999 -> 5, >=1000000 -> 4; max 17; 3/5/10-year HCC percent from Yang 2011 score table", "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "max_score": 17, "risk_10y_percent": 0, "risk_3y_percent": 0, "risk_5y_percent": 0, "score": 0, "sex": "female" } ], "path": "/api/calc/reach_b" }, "type": "json" } }, "schema": { "$schema": "https://json-schema.org/draft/2020-12/schema", "properties": { "input": { "additionalProperties": false, "properties": { "body": { "additionalProperties": false, "properties": { "items": { "items": { "properties": { "age": { "description": "Age in years. Yang 2011 derivation 30-65 only: 30-34 scores 0; 35-39 scores 1; 40-44 scores 2; 45-49 scores 3; 50-54 scores 4; 55-59 scores 5; 60-65 scores 6. Age 34 scores 0; 35 scores 1; 65 scores 6. Age outside 30-65 is rejected. This tool does not score age >=65 as 7.", "type": "integer" }, "alt_u_l": { "description": "Alanine aminotransferase in U/L (1-10000). Caller-assigned; magent does not assay ALT. Yang 2011: <15 scores 0; 15-44 scores 1; >=45 scores 2. ALT 14 scores 0; 15 and 44 score 1; 45 scores 2.", "type": "number" }, "hbeag_positive": { "description": "HBeAg positive as assigned by the caller (Yang 2011). true scores 2; false scores 0. magent does not assay HBeAg.", "type": "boolean" }, "hbv_dna_copies_per_ml": { "description": "HBV DNA in copies/mL (integer 0-10000000000). Yang 2011 uses copies/mL, not IU/mL. magent does not assay HBV DNA and does not convert units. <300 scores 0; 300-9999 scores 0; 10000-99999 scores 3; 100000-999999 scores 5; >=1000000 scores 4 (non-monotonic: 10^6 scores 4, 10^5 to 10^6-1 scores 5).", "type": "integer" }, "sex": { "description": "female or male. Yang 2011: female scores 0; male scores 2.", "enum": [ "female", "male" ], "type": "string" } }, "required": [ "sex", "age", "alt_u_l", "hbeag_positive", "hbv_dna_copies_per_ml" ], "type": "object" }, "maxItems": 25, "minItems": 1, "type": "array" } }, "required": [ "items" ], "type": "object" }, "headers": { "additionalProperties": { "type": "string" }, "type": "object" }, "method": { "const": "POST", "type": "string" }, "type": { "const": "http", "type": "string" } }, "required": [ "type", "method" ], "type": "object" }, "output": { "properties": { "example": { "type": "object" }, "type": { "type": "string" } }, "required": [ "type" ], "type": "object" } }, "required": [ "input" ], "type": "object" } } }, "tags": [ "reach-b", "hcc", "hepatitis-b", "liver", "calculator", "bazaar" ], "sourceHost": "api.magentlab.com", "lastUpdated": "2026-10-13T12:06:48.036Z", "quality": { "calls30d": 5, "uniquePayers30d": 2, "lastCalledAt": "2026-10-13T12:06:47.764Z" }, "metadata": { "serviceName": "magent", "extensions": { "bazaar": { "info": { "iconUrl": "https://api.magentlab.com/favicon.ico", "input": { "body": { "items": [ { "age": 30, "alt_u_l": 14, "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "sex": "female" }, { "age": 30, "alt_u_l": 14, "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "sex": "female" } ] }, "method": "POST", "type": "http" }, "output": { "example": { "count": 2, "items": [ { "age_years": 30, "alt_u_l": 14, "citation": { "authors": "Yang HI, Yuen MF, Chan HL, et al", "doi": "10.1016/S1470-2045(11)70077-8", "id": "yang-2011", "pmid": "21497551", "source": "Lancet Oncol. 2011;12(6):568-574", "title": "Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score" }, "components": [ { "factor": "sex", "points": 0, "present": false, "value": "female" }, { "factor": "age", "points": 0, "present": false, "value": 30 }, { "factor": "alt", "points": 0, "present": false, "value": 14 }, { "factor": "hbeag", "points": 0, "present": false }, { "factor": "hbv_dna", "points": 0, "present": false, "value": 200 } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "formula": "reach_b", "formula_expression": "REACH-B = sex + age + ALT + HBeAg + HBV DNA copies/mL; female 0, male 2; age 30-34 -> 0, 35-39 -> 1, 40-44 -> 2, 45-49 -> 3, 50-54 -> 4, 55-59 -> 5, 60-65 -> 6; ALT <15 -> 0, 15-44 -> 1, >=45 -> 2; HBeAg positive 2; HBV DNA copies/mL <300 -> 0, 300-9999 -> 0, 10000-99999 -> 3, 100000-999999 -> 5, >=1000000 -> 4; max 17; 3/5/10-year HCC percent from Yang 2011 score table", "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "max_score": 17, "risk_10y_percent": 0, "risk_3y_percent": 0, "risk_5y_percent": 0, "score": 0, "sex": "female" }, { "age_years": 30, "alt_u_l": 14, "citation": { "authors": "Yang HI, Yuen MF, Chan HL, et al", "doi": "10.1016/S1470-2045(11)70077-8", "id": "yang-2011", "pmid": "21497551", "source": "Lancet Oncol. 2011;12(6):568-574", "title": "Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score" }, "components": [ { "factor": "sex", "points": 0, "present": false, "value": "female" }, { "factor": "age", "points": 0, "present": false, "value": 30 }, { "factor": "alt", "points": 0, "present": false, "value": 14 }, { "factor": "hbeag", "points": 0, "present": false }, { "factor": "hbv_dna", "points": 0, "present": false, "value": 200 } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "formula": "reach_b", "formula_expression": "REACH-B = sex + age + ALT + HBeAg + HBV DNA copies/mL; female 0, male 2; age 30-34 -> 0, 35-39 -> 1, 40-44 -> 2, 45-49 -> 3, 50-54 -> 4, 55-59 -> 5, 60-65 -> 6; ALT <15 -> 0, 15-44 -> 1, >=45 -> 2; HBeAg positive 2; HBV DNA copies/mL <300 -> 0, 300-9999 -> 0, 10000-99999 -> 3, 100000-999999 -> 5, >=1000000 -> 4; max 17; 3/5/10-year HCC percent from Yang 2011 score table", "hbeag_positive": false, "hbv_dna_copies_per_ml": 200, "max_score": 17, "risk_10y_percent": 0, "risk_3y_percent": 0, "risk_5y_percent": 0, "score": 0, "sex": "female" } ], "path": "/api/calc/reach_b" }, "type": "json" } }, "schema": { "$schema": "https://json-schema.org/draft/2020-12/schema", "properties": { "input": { "additionalProperties": false, "properties": { "body": { "additionalProperties": false, "properties": { "items": { "items": { "properties": { "age": { "description": "Age in years. Yang 2011 derivation 30-65 only: 30-34 scores 0; 35-39 scores 1; 40-44 scores 2; 45-49 scores 3; 50-54 scores 4; 55-59 scores 5; 60-65 scores 6. Age 34 scores 0; 35 scores 1; 65 scores 6. Age outside 30-65 is rejected. This tool does not score age >=65 as 7.", "type": "integer" }, "alt_u_l": { "description": "Alanine aminotransferase in U/L (1-10000). Caller-assigned; magent does not assay ALT. Yang 2011: <15 scores 0; 15-44 scores 1; >=45 scores 2. ALT 14 scores 0; 15 and 44 score 1; 45 scores 2.", "type": "number" }, "hbeag_positive": { "description": "HBeAg positive as assigned by the caller (Yang 2011). true scores 2; false scores 0. magent does not assay HBeAg.", "type": "boolean" }, "hbv_dna_copies_per_ml": { "description": "HBV DNA in copies/mL (integer 0-10000000000). Yang 2011 uses copies/mL, not IU/mL. magent does not assay HBV DNA and does not convert units. <300 scores 0; 300-9999 scores 0; 10000-99999 scores 3; 100000-999999 scores 5; >=1000000 scores 4 (non-monotonic: 10^6 scores 4, 10^5 to 10^6-1 scores 5).", "type": "integer" }, "sex": { "description": "female or male. Yang 2011: female scores 0; male scores 2.", "enum": [ "female", "male" ], "type": "string" } }, "required": [ "sex", "age", "alt_u_l", "hbeag_positive", "hbv_dna_copies_per_ml" ], "type": "object" }, "maxItems": 25, "minItems": 1, "type": "array" } }, "required": [ "items" ], "type": "object" }, "headers": { "additionalProperties": { "type": "string" }, "type": "object" }, "method": { "const": "POST", "type": "string" }, "type": { "const": "http", "type": "string" } }, "required": [ "type", "method" ], "type": "object" }, "output": { "properties": { "example": { "type": "object" }, "type": { "type": "string" } }, "required": [ "type" ], "type": "object" } }, "required": [ "input" ], "type": "object" } } } }, "liveness": { "reliability": null }, "verified": false, "featured": false, "provider": { "host": "api.magentlab.com", "manifest_name": "api.magentlab.com", "source": "cdp-mirror", "source_manifest_url": "https://api.cdp.coinbase.com/platform/v2/x402/discovery/resources", "submitted_at": "2026-10-14T01:15:01.050Z" }, "exampleResponse": { "example": {}, "type": "string" } }