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  "description": "Popoveniuc 2014 myxedema coma points from caller-assigned bands: thermoregulatory 0/10/20; CNS 0/10/15/20/30; GI 0/5/15/20; precipitant 10; bradycardia 0/10/20/30 plus other EKG 10, effusion 10, pulmonary edema 15, cardiomegaly 15, hypotension 20; five metabolic flags 10 each. Max 230. ≥60 potentially diagnostic; 45–59 at risk. Not a diagnosis or thyroid-hormone order. magent does not measure temperature, GCS, or labs.",
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                  "authors": "Popoveniuc G, Chandra T, Sud A, Sharma M, Blackman MR, Burman KD, Mete M, Desale S, Wartofsky L",
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                  "source": "Endocr Pract. 2014;20(8):808-817",
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                    "factor": "pericardial_pleural_effusion",
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                    "factor": "cardiomegaly",
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                    "factor": "hypotension",
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                    "factor": "hyponatremia",
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                          "description": "Cardiomegaly as assigned by the caller (true or false). Popoveniuc 2014: true → 15. magent does not interpret imaging.",
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                          "description": "Caller-assigned Popoveniuc 2014 central-nervous-system band. absent scores 0; somnolent_lethargic 10; obtunded 15; stupor 20; coma_seizures 30. magent does not compute GCS or examine the patient.",
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                          "description": "Decrease in glomerular filtration rate as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not compute GFR.",
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                          "description": "Caller-assigned Popoveniuc 2014 gastrointestinal band. absent scores 0; anorexia_pain_constipation (anorexia, abdominal pain, or constipation) scores 5; decreased_motility 15; paralytic_ileus 20. magent does not examine the patient.",
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                          "description": "Hypotension or shock as assigned by the caller (true or false). Popoveniuc 2014: true → 20. magent does not measure blood pressure.",
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                          "description": "Hypoxemia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure oxygen.",
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                          "description": "Other electrocardiogram changes as assigned by the caller (true or false): QT prolongation, low voltage, bundle-branch block, nonspecific ST-T changes, or heart block (Popoveniuc 2014). true → 10. magent does not read an ECG.",
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                          "description": "Precipitating event as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not take a history.",
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                          "description": "Caller-assigned Popoveniuc 2014 thermoregulatory band. gt_35 (>35 °C) scores 0; 32_to_35 (32–35 °C) scores 10; lt_32 (<32 °C) scores 20. magent does not measure temperature.",
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    "myxedema-coma",
    "hypothyroidism",
    "electrolytes",
    "popoveniuc",
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  "sourceHost": "api.magentlab.com",
  "lastUpdated": "2026-10-13T09:36:09.915Z",
  "quality": {
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    "uniquePayers30d": 2,
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                  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
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                  "formula_expression": "Popoveniuc 2014 = thermoregulatory(gt_35→0, 32_to_35→10, lt_32→20) + cns_effects(absent→0, somnolent_lethargic→10, obtunded→15, stupor→20, coma_seizures→30) + gastrointestinal(absent→0, anorexia_pain_constipation→5, decreased_motility→15, paralytic_ileus→20) + 10*precipitating_event + bradycardia(absent→0, 50_to_59→10, 40_to_49→20, lt_40→30) + 10*other_ekg_changes + 10*pericardial_pleural_effusion + 15*pulmonary_edema + 15*cardiomegaly + 20*hypotension + 10*hyponatremia + 10*hypoglycemia + 10*hypoxemia + 10*hypercarbia + 10*decreased_gfr; max 230; ≥60 potentially_diagnostic, 45–59 at_risk",
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                    "authors": "Popoveniuc G, Chandra T, Sud A, Sharma M, Blackman MR, Burman KD, Mete M, Desale S, Wartofsky L",
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                  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
                  "formula": "myxedema_coma",
                  "formula_expression": "Popoveniuc 2014 = thermoregulatory(gt_35→0, 32_to_35→10, lt_32→20) + cns_effects(absent→0, somnolent_lethargic→10, obtunded→15, stupor→20, coma_seizures→30) + gastrointestinal(absent→0, anorexia_pain_constipation→5, decreased_motility→15, paralytic_ileus→20) + 10*precipitating_event + bradycardia(absent→0, 50_to_59→10, 40_to_49→20, lt_40→30) + 10*other_ekg_changes + 10*pericardial_pleural_effusion + 15*pulmonary_edema + 15*cardiomegaly + 20*hypotension + 10*hyponatremia + 10*hypoglycemia + 10*hypoxemia + 10*hypercarbia + 10*decreased_gfr; max 230; ≥60 potentially_diagnostic, 45–59 at_risk",
                  "max_score": 230,
                  "myxedema_coma_band": "below_at_risk",
                  "score": 0
                }
              ],
              "path": "/api/calc/myxedema_coma"
            },
            "type": "json"
          }
        },
        "schema": {
          "$schema": "https://json-schema.org/draft/2020-12/schema",
          "properties": {
            "input": {
              "additionalProperties": false,
              "properties": {
                "body": {
                  "additionalProperties": false,
                  "properties": {
                    "items": {
                      "items": {
                        "properties": {
                          "bradycardia": {
                            "description": "Caller-assigned Popoveniuc 2014 bradycardia band. absent scores 0; 50_to_59 (heart rate 50–59) scores 10; 40_to_49 scores 20; lt_40 (<40) scores 30. magent does not measure heart rate.",
                            "enum": [
                              "absent",
                              "50_to_59",
                              "40_to_49",
                              "lt_40"
                            ],
                            "type": "string"
                          },
                          "cardiomegaly": {
                            "description": "Cardiomegaly as assigned by the caller (true or false). Popoveniuc 2014: true → 15. magent does not interpret imaging.",
                            "type": "boolean"
                          },
                          "cns_effects": {
                            "description": "Caller-assigned Popoveniuc 2014 central-nervous-system band. absent scores 0; somnolent_lethargic 10; obtunded 15; stupor 20; coma_seizures 30. magent does not compute GCS or examine the patient.",
                            "enum": [
                              "absent",
                              "somnolent_lethargic",
                              "obtunded",
                              "stupor",
                              "coma_seizures"
                            ],
                            "type": "string"
                          },
                          "decreased_gfr": {
                            "description": "Decrease in glomerular filtration rate as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not compute GFR.",
                            "type": "boolean"
                          },
                          "gastrointestinal": {
                            "description": "Caller-assigned Popoveniuc 2014 gastrointestinal band. absent scores 0; anorexia_pain_constipation (anorexia, abdominal pain, or constipation) scores 5; decreased_motility 15; paralytic_ileus 20. magent does not examine the patient.",
                            "enum": [
                              "absent",
                              "anorexia_pain_constipation",
                              "decreased_motility",
                              "paralytic_ileus"
                            ],
                            "type": "string"
                          },
                          "hypercarbia": {
                            "description": "Hypercarbia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure carbon dioxide.",
                            "type": "boolean"
                          },
                          "hypoglycemia": {
                            "description": "Hypoglycemia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure glucose.",
                            "type": "boolean"
                          },
                          "hyponatremia": {
                            "description": "Hyponatremia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure sodium.",
                            "type": "boolean"
                          },
                          "hypotension": {
                            "description": "Hypotension or shock as assigned by the caller (true or false). Popoveniuc 2014: true → 20. magent does not measure blood pressure.",
                            "type": "boolean"
                          },
                          "hypoxemia": {
                            "description": "Hypoxemia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure oxygen.",
                            "type": "boolean"
                          },
                          "other_ekg_changes": {
                            "description": "Other electrocardiogram changes as assigned by the caller (true or false): QT prolongation, low voltage, bundle-branch block, nonspecific ST-T changes, or heart block (Popoveniuc 2014). true → 10. magent does not read an ECG.",
                            "type": "boolean"
                          },
                          "pericardial_pleural_effusion": {
                            "description": "Pericardial or pleural effusion as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not interpret imaging.",
                            "type": "boolean"
                          },
                          "precipitating_event": {
                            "description": "Precipitating event as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not take a history.",
                            "type": "boolean"
                          },
                          "pulmonary_edema": {
                            "description": "Pulmonary edema as assigned by the caller (true or false). Popoveniuc 2014: true → 15. magent does not interpret imaging.",
                            "type": "boolean"
                          },
                          "thermoregulatory": {
                            "description": "Caller-assigned Popoveniuc 2014 thermoregulatory band. gt_35 (>35 °C) scores 0; 32_to_35 (32–35 °C) scores 10; lt_32 (<32 °C) scores 20. magent does not measure temperature.",
                            "enum": [
                              "gt_35",
                              "32_to_35",
                              "lt_32"
                            ],
                            "type": "string"
                          }
                        },
                        "required": [
                          "thermoregulatory",
                          "cns_effects",
                          "gastrointestinal",
                          "precipitating_event",
                          "bradycardia",
                          "other_ekg_changes",
                          "pericardial_pleural_effusion",
                          "pulmonary_edema",
                          "cardiomegaly",
                          "hypotension",
                          "hyponatremia",
                          "hypoglycemia",
                          "hypoxemia",
                          "hypercarbia",
                          "decreased_gfr"
                        ],
                        "type": "object"
                      },
                      "maxItems": 25,
                      "minItems": 1,
                      "type": "array"
                    }
                  },
                  "required": [
                    "items"
                  ],
                  "type": "object"
                },
                "headers": {
                  "additionalProperties": {
                    "type": "string"
                  },
                  "type": "object"
                },
                "method": {
                  "const": "POST",
                  "type": "string"
                },
                "type": {
                  "const": "http",
                  "type": "string"
                }
              },
              "required": [
                "type",
                "method"
              ],
              "type": "object"
            },
            "output": {
              "properties": {
                "example": {
                  "type": "object"
                },
                "type": {
                  "type": "string"
                }
              },
              "required": [
                "type"
              ],
              "type": "object"
            }
          },
          "required": [
            "input"
          ],
          "type": "object"
        }
      }
    }
  },
  "liveness": {
    "reliability": null
  },
  "verified": false,
  "featured": false,
  "provider": {
    "host": "api.magentlab.com",
    "manifest_name": "api.magentlab.com",
    "source": "cdp-mirror",
    "source_manifest_url": "https://api.cdp.coinbase.com/platform/v2/x402/discovery/resources",
    "submitted_at": "2026-10-14T01:15:01.050Z"
  },
  "exampleResponse": {
    "example": {},
    "type": "string"
  }
}