{
  "x402Version": 2,
  "id": 39348,
  "slug": "39348",
  "resource": "https://api.magentlab.com/api/calc/rome_iv_functional_gallbladder",
  "description": "Cotton 2016 Rome IV E1a functional gallbladder disorder. rome_iv_functional_gallbladder is true iff nested E1 biliary pain and absence of gallstones or other structural pathology. low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required. Caller assigns nine flags. magent does not read ultrasound, EUS, or HIDA or decide cholecystectomy. Not a diagnosis, not biliary SOD, not pancreatic SOD.",
  "type": "http",
  "serviceName": "magent",
  "resourceType": "Agent Service",
  "accepts": [
    {
      "scheme": "exact",
      "network": "eip155:8453",
      "payTo": "0x836Be278f1739fB4308091cD1852F7971Bc19Ee2",
      "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
      "amount": "5000",
      "amountUsd": 0.005,
      "maxTimeoutSeconds": 600
    }
  ],
  "outputSchema": {
    "properties": {
      "example": {
        "type": "object"
      },
      "type": {
        "type": "string"
      }
    },
    "required": [
      "type"
    ],
    "type": "object"
  },
  "extensions": {
    "bazaar": {
      "info": {
        "iconUrl": "https://api.magentlab.com/favicon.ico",
        "input": {
          "body": {
            "items": [
              {
                "absence_of_gallstones_or_other_structural_pathology": true,
                "builds_to_steady_level_lasts_30_min_or_longer": true,
                "epigastric_or_ruq_pain": true,
                "low_ef_on_gallbladder_scintigraphy": true,
                "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                "not_significantly_related_to_bowel_movements": true,
                "not_significantly_relieved_by_postural_change_or_acid_suppression": true,
                "occurring_at_different_intervals_not_daily": true,
                "severe_enough_to_interrupt_activities_or_ed_visit": true
              },
              {
                "absence_of_gallstones_or_other_structural_pathology": true,
                "builds_to_steady_level_lasts_30_min_or_longer": true,
                "epigastric_or_ruq_pain": true,
                "low_ef_on_gallbladder_scintigraphy": true,
                "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                "not_significantly_related_to_bowel_movements": true,
                "not_significantly_relieved_by_postural_change_or_acid_suppression": true,
                "occurring_at_different_intervals_not_daily": true,
                "severe_enough_to_interrupt_activities_or_ed_visit": true
              }
            ]
          },
          "method": "POST",
          "type": "http"
        },
        "output": {
          "example": {
            "count": 2,
            "items": [
              {
                "citation": {
                  "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
                  "doi": "10.1053/j.gastro.2016.02.033",
                  "id": "cotton-2016",
                  "pmid": "27144629",
                  "source": "Gastroenterology. 2016;150(6):1420-1429",
                  "title": "Gallbladder and Sphincter of Oddi Disorders"
                },
                "criteria": [
                  {
                    "factor": "epigastric_or_ruq_pain",
                    "met": true
                  },
                  {
                    "factor": "builds_to_steady_level_lasts_30_min_or_longer",
                    "met": true
                  },
                  {
                    "factor": "occurring_at_different_intervals_not_daily",
                    "met": true
                  },
                  {
                    "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
                    "met": true
                  },
                  {
                    "factor": "not_significantly_related_to_bowel_movements",
                    "met": true
                  },
                  {
                    "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
                    "met": true
                  },
                  {
                    "factor": "absence_of_gallstones_or_other_structural_pathology",
                    "met": true
                  },
                  {
                    "factor": "low_ef_on_gallbladder_scintigraphy",
                    "met": true
                  },
                  {
                    "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
                    "met": true
                  }
                ],
                "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
                "formula": "rome_iv_functional_gallbladder",
                "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
                "low_ef_on_gallbladder_scintigraphy": true,
                "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                "rome_iv_functional_gallbladder": true
              },
              {
                "citation": {
                  "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
                  "doi": "10.1053/j.gastro.2016.02.033",
                  "id": "cotton-2016",
                  "pmid": "27144629",
                  "source": "Gastroenterology. 2016;150(6):1420-1429",
                  "title": "Gallbladder and Sphincter of Oddi Disorders"
                },
                "criteria": [
                  {
                    "factor": "epigastric_or_ruq_pain",
                    "met": true
                  },
                  {
                    "factor": "builds_to_steady_level_lasts_30_min_or_longer",
                    "met": true
                  },
                  {
                    "factor": "occurring_at_different_intervals_not_daily",
                    "met": true
                  },
                  {
                    "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
                    "met": true
                  },
                  {
                    "factor": "not_significantly_related_to_bowel_movements",
                    "met": true
                  },
                  {
                    "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
                    "met": true
                  },
                  {
                    "factor": "absence_of_gallstones_or_other_structural_pathology",
                    "met": true
                  },
                  {
                    "factor": "low_ef_on_gallbladder_scintigraphy",
                    "met": true
                  },
                  {
                    "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
                    "met": true
                  }
                ],
                "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
                "formula": "rome_iv_functional_gallbladder",
                "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
                "low_ef_on_gallbladder_scintigraphy": true,
                "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                "rome_iv_functional_gallbladder": true
              }
            ],
            "path": "/api/calc/rome_iv_functional_gallbladder"
          },
          "type": "json"
        }
      },
      "schema": {
        "$schema": "https://json-schema.org/draft/2020-12/schema",
        "properties": {
          "input": {
            "additionalProperties": false,
            "properties": {
              "body": {
                "additionalProperties": false,
                "properties": {
                  "items": {
                    "items": {
                      "properties": {
                        "absence_of_gallstones_or_other_structural_pathology": {
                          "description": "Absence of gallstones or other structural pathology, as assigned (Cotton 2016 Rome IV E1a). true or false as assigned by the caller. magent does not read ultrasound, EUS, or other imaging.",
                          "type": "boolean"
                        },
                        "builds_to_steady_level_lasts_30_min_or_longer": {
                          "description": "Pain builds to a steady level and lasts 30 minutes or longer, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                          "type": "boolean"
                        },
                        "epigastric_or_ruq_pain": {
                          "description": "Epigastric or right upper quadrant pain, as assigned (Cotton 2016 Rome IV E1 biliary pain). true or false as assigned by the caller. magent does not examine the patient.",
                          "type": "boolean"
                        },
                        "low_ef_on_gallbladder_scintigraphy": {
                          "description": "Low ejection fraction on gallbladder scintigraphy, a supportive criterion that is not required for rome_iv_functional_gallbladder (Cotton 2016). true or false as assigned by the caller. magent does not read HIDA or decide cholecystectomy.",
                          "type": "boolean"
                        },
                        "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": {
                          "description": "Normal liver enzymes, conjugated bilirubin, and amylase/lipase, a supportive criterion that is not required for rome_iv_functional_gallbladder (Cotton 2016). true or false as assigned by the caller. magent does not read laboratory results.",
                          "type": "boolean"
                        },
                        "not_significantly_related_to_bowel_movements": {
                          "description": "Pain not significantly related to bowel movements, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                          "type": "boolean"
                        },
                        "not_significantly_relieved_by_postural_change_or_acid_suppression": {
                          "description": "Pain not significantly relieved by postural change or acid suppression, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                          "type": "boolean"
                        },
                        "occurring_at_different_intervals_not_daily": {
                          "description": "Pain occurring at different intervals (not daily), as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                          "type": "boolean"
                        },
                        "severe_enough_to_interrupt_activities_or_ed_visit": {
                          "description": "Pain severe enough to interrupt usual activities or lead to an emergency department visit, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                          "type": "boolean"
                        }
                      },
                      "required": [
                        "epigastric_or_ruq_pain",
                        "builds_to_steady_level_lasts_30_min_or_longer",
                        "occurring_at_different_intervals_not_daily",
                        "severe_enough_to_interrupt_activities_or_ed_visit",
                        "not_significantly_related_to_bowel_movements",
                        "not_significantly_relieved_by_postural_change_or_acid_suppression",
                        "absence_of_gallstones_or_other_structural_pathology",
                        "low_ef_on_gallbladder_scintigraphy",
                        "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase"
                      ],
                      "type": "object"
                    },
                    "maxItems": 25,
                    "minItems": 1,
                    "type": "array"
                  }
                },
                "required": [
                  "items"
                ],
                "type": "object"
              },
              "headers": {
                "additionalProperties": {
                  "type": "string"
                },
                "type": "object"
              },
              "method": {
                "const": "POST",
                "type": "string"
              },
              "type": {
                "const": "http",
                "type": "string"
              }
            },
            "required": [
              "type",
              "method"
            ],
            "type": "object"
          },
          "output": {
            "properties": {
              "example": {
                "type": "object"
              },
              "type": {
                "type": "string"
              }
            },
            "required": [
              "type"
            ],
            "type": "object"
          }
        },
        "required": [
          "input"
        ],
        "type": "object"
      }
    }
  },
  "tags": [
    "rome-iv-fgbd",
    "functional-gallbladder",
    "gi",
    "biliary",
    "rome-iv",
    "bazaar"
  ],
  "sourceHost": "api.magentlab.com",
  "lastUpdated": "2026-10-13T13:21:46.982Z",
  "quality": {
    "calls30d": 5,
    "uniquePayers30d": 2,
    "lastCalledAt": "2026-10-13T13:21:46.787Z"
  },
  "metadata": {
    "serviceName": "magent",
    "extensions": {
      "bazaar": {
        "info": {
          "iconUrl": "https://api.magentlab.com/favicon.ico",
          "input": {
            "body": {
              "items": [
                {
                  "absence_of_gallstones_or_other_structural_pathology": true,
                  "builds_to_steady_level_lasts_30_min_or_longer": true,
                  "epigastric_or_ruq_pain": true,
                  "low_ef_on_gallbladder_scintigraphy": true,
                  "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                  "not_significantly_related_to_bowel_movements": true,
                  "not_significantly_relieved_by_postural_change_or_acid_suppression": true,
                  "occurring_at_different_intervals_not_daily": true,
                  "severe_enough_to_interrupt_activities_or_ed_visit": true
                },
                {
                  "absence_of_gallstones_or_other_structural_pathology": true,
                  "builds_to_steady_level_lasts_30_min_or_longer": true,
                  "epigastric_or_ruq_pain": true,
                  "low_ef_on_gallbladder_scintigraphy": true,
                  "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                  "not_significantly_related_to_bowel_movements": true,
                  "not_significantly_relieved_by_postural_change_or_acid_suppression": true,
                  "occurring_at_different_intervals_not_daily": true,
                  "severe_enough_to_interrupt_activities_or_ed_visit": true
                }
              ]
            },
            "method": "POST",
            "type": "http"
          },
          "output": {
            "example": {
              "count": 2,
              "items": [
                {
                  "citation": {
                    "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
                    "doi": "10.1053/j.gastro.2016.02.033",
                    "id": "cotton-2016",
                    "pmid": "27144629",
                    "source": "Gastroenterology. 2016;150(6):1420-1429",
                    "title": "Gallbladder and Sphincter of Oddi Disorders"
                  },
                  "criteria": [
                    {
                      "factor": "epigastric_or_ruq_pain",
                      "met": true
                    },
                    {
                      "factor": "builds_to_steady_level_lasts_30_min_or_longer",
                      "met": true
                    },
                    {
                      "factor": "occurring_at_different_intervals_not_daily",
                      "met": true
                    },
                    {
                      "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
                      "met": true
                    },
                    {
                      "factor": "not_significantly_related_to_bowel_movements",
                      "met": true
                    },
                    {
                      "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
                      "met": true
                    },
                    {
                      "factor": "absence_of_gallstones_or_other_structural_pathology",
                      "met": true
                    },
                    {
                      "factor": "low_ef_on_gallbladder_scintigraphy",
                      "met": true
                    },
                    {
                      "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
                      "met": true
                    }
                  ],
                  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
                  "formula": "rome_iv_functional_gallbladder",
                  "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
                  "low_ef_on_gallbladder_scintigraphy": true,
                  "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                  "rome_iv_functional_gallbladder": true
                },
                {
                  "citation": {
                    "authors": "Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES",
                    "doi": "10.1053/j.gastro.2016.02.033",
                    "id": "cotton-2016",
                    "pmid": "27144629",
                    "source": "Gastroenterology. 2016;150(6):1420-1429",
                    "title": "Gallbladder and Sphincter of Oddi Disorders"
                  },
                  "criteria": [
                    {
                      "factor": "epigastric_or_ruq_pain",
                      "met": true
                    },
                    {
                      "factor": "builds_to_steady_level_lasts_30_min_or_longer",
                      "met": true
                    },
                    {
                      "factor": "occurring_at_different_intervals_not_daily",
                      "met": true
                    },
                    {
                      "factor": "severe_enough_to_interrupt_activities_or_ed_visit",
                      "met": true
                    },
                    {
                      "factor": "not_significantly_related_to_bowel_movements",
                      "met": true
                    },
                    {
                      "factor": "not_significantly_relieved_by_postural_change_or_acid_suppression",
                      "met": true
                    },
                    {
                      "factor": "absence_of_gallstones_or_other_structural_pathology",
                      "met": true
                    },
                    {
                      "factor": "low_ef_on_gallbladder_scintigraphy",
                      "met": true
                    },
                    {
                      "factor": "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase",
                      "met": true
                    }
                  ],
                  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
                  "formula": "rome_iv_functional_gallbladder",
                  "formula_expression": "rome_iv_functional_gallbladder iff epigastric_or_ruq_pain and builds_to_steady_level_lasts_30_min_or_longer and occurring_at_different_intervals_not_daily and severe_enough_to_interrupt_activities_or_ed_visit and not_significantly_related_to_bowel_movements and not_significantly_relieved_by_postural_change_or_acid_suppression and absence_of_gallstones_or_other_structural_pathology (Cotton 2016 Rome IV E1a). low_ef_on_gallbladder_scintigraphy and normal_liver_enzymes_conjugated_bilirubin_amylase_lipase are supportive and not required.",
                  "low_ef_on_gallbladder_scintigraphy": true,
                  "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": true,
                  "rome_iv_functional_gallbladder": true
                }
              ],
              "path": "/api/calc/rome_iv_functional_gallbladder"
            },
            "type": "json"
          }
        },
        "schema": {
          "$schema": "https://json-schema.org/draft/2020-12/schema",
          "properties": {
            "input": {
              "additionalProperties": false,
              "properties": {
                "body": {
                  "additionalProperties": false,
                  "properties": {
                    "items": {
                      "items": {
                        "properties": {
                          "absence_of_gallstones_or_other_structural_pathology": {
                            "description": "Absence of gallstones or other structural pathology, as assigned (Cotton 2016 Rome IV E1a). true or false as assigned by the caller. magent does not read ultrasound, EUS, or other imaging.",
                            "type": "boolean"
                          },
                          "builds_to_steady_level_lasts_30_min_or_longer": {
                            "description": "Pain builds to a steady level and lasts 30 minutes or longer, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                            "type": "boolean"
                          },
                          "epigastric_or_ruq_pain": {
                            "description": "Epigastric or right upper quadrant pain, as assigned (Cotton 2016 Rome IV E1 biliary pain). true or false as assigned by the caller. magent does not examine the patient.",
                            "type": "boolean"
                          },
                          "low_ef_on_gallbladder_scintigraphy": {
                            "description": "Low ejection fraction on gallbladder scintigraphy, a supportive criterion that is not required for rome_iv_functional_gallbladder (Cotton 2016). true or false as assigned by the caller. magent does not read HIDA or decide cholecystectomy.",
                            "type": "boolean"
                          },
                          "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase": {
                            "description": "Normal liver enzymes, conjugated bilirubin, and amylase/lipase, a supportive criterion that is not required for rome_iv_functional_gallbladder (Cotton 2016). true or false as assigned by the caller. magent does not read laboratory results.",
                            "type": "boolean"
                          },
                          "not_significantly_related_to_bowel_movements": {
                            "description": "Pain not significantly related to bowel movements, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                            "type": "boolean"
                          },
                          "not_significantly_relieved_by_postural_change_or_acid_suppression": {
                            "description": "Pain not significantly relieved by postural change or acid suppression, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                            "type": "boolean"
                          },
                          "occurring_at_different_intervals_not_daily": {
                            "description": "Pain occurring at different intervals (not daily), as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                            "type": "boolean"
                          },
                          "severe_enough_to_interrupt_activities_or_ed_visit": {
                            "description": "Pain severe enough to interrupt usual activities or lead to an emergency department visit, as assigned (Cotton 2016 E1). true or false as assigned by the caller. magent does not take a history.",
                            "type": "boolean"
                          }
                        },
                        "required": [
                          "epigastric_or_ruq_pain",
                          "builds_to_steady_level_lasts_30_min_or_longer",
                          "occurring_at_different_intervals_not_daily",
                          "severe_enough_to_interrupt_activities_or_ed_visit",
                          "not_significantly_related_to_bowel_movements",
                          "not_significantly_relieved_by_postural_change_or_acid_suppression",
                          "absence_of_gallstones_or_other_structural_pathology",
                          "low_ef_on_gallbladder_scintigraphy",
                          "normal_liver_enzymes_conjugated_bilirubin_amylase_lipase"
                        ],
                        "type": "object"
                      },
                      "maxItems": 25,
                      "minItems": 1,
                      "type": "array"
                    }
                  },
                  "required": [
                    "items"
                  ],
                  "type": "object"
                },
                "headers": {
                  "additionalProperties": {
                    "type": "string"
                  },
                  "type": "object"
                },
                "method": {
                  "const": "POST",
                  "type": "string"
                },
                "type": {
                  "const": "http",
                  "type": "string"
                }
              },
              "required": [
                "type",
                "method"
              ],
              "type": "object"
            },
            "output": {
              "properties": {
                "example": {
                  "type": "object"
                },
                "type": {
                  "type": "string"
                }
              },
              "required": [
                "type"
              ],
              "type": "object"
            }
          },
          "required": [
            "input"
          ],
          "type": "object"
        }
      }
    }
  },
  "liveness": {
    "reliability": null
  },
  "verified": false,
  "featured": false,
  "provider": {
    "host": "api.magentlab.com",
    "manifest_name": "api.magentlab.com",
    "source": "cdp-mirror",
    "source_manifest_url": "https://api.cdp.coinbase.com/platform/v2/x402/discovery/resources",
    "submitted_at": "2026-10-14T01:15:01.050Z"
  },
  "exampleResponse": {
    "example": {},
    "type": "string"
  }
}