Agent Service · x402 · early usage

2024 McDonald typical CIS (Montalban 2025)

by api.magentlab.com · discovered, not yet claimed by its owner · updated 2026-10-12

30d calls4

30d payers2

MethodPOST

Outputjson

Mirrored from Coinbase's public x402 Bazaar. The description is the provider's own text and has not been reviewed here; the payment requirements are copied as published.

What it does

2024 McDonald typical CIS (Montalban 2025). mcdonald_ms iff typical_cis and no_better_explanation and: ≥2 attacks with ≥2 lesions; or ≥2 attacks with one lesion plus DIS; or CIS with ≥2 lesions plus MRI DIT, OCB, or kappa FLC; or CIS with one lesion plus DIS and MRI DIT, OCB, or kappa FLC. DIS = ≥2 of 5 topographies (optic nerve added). Kappa FLC interchangeable with OCB. Not 2017 McDonald. Not PPMS. Not RIS. magent does not read MRI or assay CSF. Not a diagnosis. Not a medical device.

Tags: mcdonald-2024 · multiple-sclerosis · neurology · cis · calculator · bazaar

Call contract

Method: POST
Input: HTTP request
Output: json
Last paid call: 2026-10-12

Input example from Bazaar metadata

{
  "items": [
    {
      "cortical_or_juxtacortical": false,
      "csf_kflc": false,
      "csf_specific_ocb": false,
      "dit_mri": false,
      "infratentorial": false,
      "no_better_explanation": true,
      "optic_nerve": false,
      "periventricular": false,
      "spinal_cord": false,
      "two_or_more_attacks": true,
      "two_or_more_lesions": true,
      "typical_cis": true
    },
    {
      "cortical_or_juxtacortical": false,
      "csf_kflc": false,
      "csf_specific_ocb": false,
      "dit_mri": false,
      "infratentorial": false,
      "no_better_explanation": true,
      "optic_nerve": false,
      "periventricular": false,
      "spinal_cord": false,
      "two_or_more_attacks": true,
      "two_or_more_lesions": true,
      "typical_cis": true
    }
  ]
}

Output example

{
  "count": 2,
  "items": [
    {
      "citation": {
        "authors": "Montalban X, Lebrun-Frénay C, Oh J, et al.",
        "doi": "10.1016/S1474-4422(25)00270-4",
        "id": "montalban-2025",
        "pmid": "40975101",
        "source": "Lancet Neurol. 2025;24(10):850-865",
        "title": "Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria"
      },
      "cortical_or_juxtacortical": false,
      "criteria": [
        {
          "factor": "typical_cis",
          "met": true
        },
        {
          "factor": "no_better_explanation",
          "met": true
        },
        {
          "factor": "two_or_more_attacks",
          "met": true
        },
        {
          "factor": "two_or_more_lesions",
          "met": true
        },
        {
          "factor": "periventricular",
          "met": false
        },
        {
          "factor": "cortical_or_juxtacortical",
          "met": false
        },
        {
          "factor": "infratentorial",
          "met": false
        },
        {
          "factor": "spinal_cord",
          "met": false
        },
        {
          "factor": "optic_nerve",
          "met": false
        },
        {
          "factor": "dis",
          "met": false
        },
        {
          "factor": "dit_mri",
          "met": false
        },
        {
          "factor": "csf_specific_ocb",
          "met": false
        },
        {
          "factor": "csf_kflc",
          "met": false
        },
        {
          "factor": "relapsing_cis_pathway",
          "met": true
        },
        {
          "factor": "mcdonald_ms",
          "met": true
        }
      ],
      "csf_kflc": false,
      "csf_specific_ocb": false,
      "dis": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "dit_mri": false,
      "formula": "mcdonald_2024",
      "formula_expression": "mcdonald_ms iff typical_cis and no_better_explanation and ((two_or_more_attacks and two_or_more_lesions) or (two_or_more_attacks and not two_or_more_lesions and dis) or (not two_or_more_attacks and two_or_more_lesions and (dit_mri or csf_specific_ocb or csf_kflc)) or (not two_or_more_attacks and not two_or_more_lesions and dis and (dit_mri or csf_specific_ocb or csf_kflc))) (Montalban 2025 / 2024 McDonald typical CIS). dis is true iff at least two of periventricular, cortical_or_juxtacortical, infratentorial, spinal_cord, optic_nerve are true. CSF kappa free-light chains are interchangeable with CSF-specific OCB as the CSF DIT substitute. Not PPMS. Not RIS. Not 2017 McDonald. magent does not read MRI, OCT, VEP, or assay CSF. Not a diagnosis",
      "infratentorial": false,
      "mcdonald_ms": true,
      "no_better_explanation": true,
      "optic_nerve": false,
      "periventricular": false,
      "spinal_cord": false,
      "two_or_more_attacks": true,
      "two_or_more_lesions": true,
      "typical_cis": true
    },
    {
      "citation": {
        "authors": "Montalban X, Lebrun-Frénay C, Oh J, et al.",
        "doi": "10.1016/S1474-4422(25)00270-4",
        "id": "montalban-2025",
        "pmid": "40975101",
        "source": "Lancet Neurol. 2025;24(10):850-865",
        "title": "Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria"
      },
      "cortical_or_juxtacortical": false,
      "criteria": [
        {
          "factor": "typical_cis",
          "met": true
        },
        {
          "factor": "no_better_explanation",
          "met": true
        },
        {
          "factor": "two_or_more_attacks",
          "met": true
        },
        {
          "factor": "two_or_more_lesions",
          "met": true
        },
        {
          "factor": "periventricular",
          "met": false
        },
        {
          "factor": "cortical_or_juxtacortical",
          "met": false
        },
        {
          "factor": "infratentorial",
          "met": false
        },
        {
          "factor": "spinal_cord",
          "met": false
        },
        {
          "factor": "optic_nerve",
          "met": false
        },
        {
          "factor": "dis",
          "met": false
        },
        {
          "factor": "dit_mri",
          "met": false
        },
        {
          "factor": "csf_specific_ocb",
          "met": false
        },
        {
          "factor": "csf_kflc",
          "met": false
        },
        {
          "factor": "relapsing_cis_pathway",
          "met": true
        },
        {
          "factor": "mcdonald_ms",
          "met": true
        }
      ],
      "csf_kflc": false,
      "csf_specific_ocb": false,
      "dis": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "dit_mri": false,
      "formula": "mcdonald_2024",
      "formula_expression": "mcdonald_ms iff typical_cis and no_better_explanation and ((two_or_more_attacks and two_or_more_lesions) or (two_or_more_attacks and not two_or_more_lesions and dis) or (not two_or_more_attacks and two_or_more_lesions and (dit_mri or csf_specific_ocb or csf_kflc)) or (not two_or_more_attacks and not two_or_more_lesions and dis and (dit_mri or csf_specific_ocb or csf_kflc))) (Montalban 2025 / 2024 McDonald typical CIS). dis is true iff at least two of periventricular, cortical_or_juxtacortical, infratentorial, spinal_cord, optic_nerve are true. CSF kappa free-light chains are interchangeable with CSF-specific OCB as the CSF DIT substitute. Not PPMS. Not RIS. Not 2017 McDonald. magent does not read MRI, OCT, VEP, or assay CSF. Not a diagnosis",
      "infratentorial": false,
      "mcdonald_ms": true,
      "no_better_explanation": true,
      "optic_nerve": false,
      "periventricular": false,
      "spinal_cord": false,
      "two_or_more_attacks": true,
      "two_or_more_lesions": true,
      "typical_cis": true
    }
  ],
  "path": "/api/calc/mcdonald_2024"
}

Use with an agent

Discover. Agents find this listing with GET https://bazaar.saylorinnovations.com/discovery/search?query=…, the MCP tool search_resources, or /discovery/resources.
Inspect. Fetch /resources/39475.json for the price and payment options.
Pay. Call GET https://api.magentlab.com/api/calc/mcdonald_2024. The provider answers 402 with its payment requirements. An x402 client signs one of the options below and retries with PAYMENT-SIGNATURE.
Execute. The provider returns 200 with the data. Agent Bazaar is not in the request path and never sees your payment.

For humans

You don't need an account or an API key; you need a wallet holding a small amount of USDC on Base, and an x402-capable client (see the examples below). Call the endpoint unpaid first to see exactly what it asks for.

Pricing & payment

Price: $0.005 / request
Protocol: x402 v2
Auth: No account or API key. Pay per request.
Networks: Base
Demand: 4 calls · 2 unique payers in 30d (public x402 Bazaar data)

x402 payment requirements

Scheme	Network	Asset	Amount	Pay to	Timeout
exact	Base eip155:8453	USDC	$0.005	0x836Be278f1739fB4308091cD1852F7971Bc19Ee2	600s

accepts[] (raw JSON)

[
  {
    "scheme": "exact",
    "network": "eip155:8453",
    "payTo": "0x836Be278f1739fB4308091cD1852F7971Bc19Ee2",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "5000",
    "amountUsd": 0.005,
    "maxTimeoutSeconds": 600
  }
]

Schemas

Output schema (JSON Schema)

{
  "properties": {
    "example": {
      "type": "object"
    },
    "type": {
      "type": "string"
    }
  },
  "required": [
    "type"
  ],
  "type": "object"
}

Example shape — generated from the schema, not a captured live response

{
  "example": {},
  "type": "string"
}

Examples

curl

curl "https://api.magentlab.com/api/calc/mcdonald_2024"
# -> 402 Payment Required, accepts[] lists how to pay
# retry with a PAYMENT-SIGNATURE (or PAYMENT header) once paid

JavaScript

const res = await fetch("https://api.magentlab.com/api/calc/mcdonald_2024");
if (res.status === 402) {
  const { accepts } = await res.json();
  // pay one of accepts[] via an x402 client, then retry with the payment header
}

Python

import httpx
res = httpx.get("https://api.magentlab.com/api/calc/mcdonald_2024")
if res.status_code == 402:
    accepts = res.json()["accepts"]
    # pay one of accepts[] via an x402 client, then retry with the payment header

Details

Provider: api.magentlab.com
Endpoint: https://api.magentlab.com/api/calc/mcdonald_2024
Machine-readable: /resources/39475.json