{ "x402Version": 2, "id": 39539, "slug": "39539", "resource": "https://api.magentlab.com/api/calc/vacs_cci", "description": "McGinnis 2024 VACS-CCI Table 2 Model 7 linear predictor from sex, age, hemoglobin, FIB-4, eGFR, albumin, WBC, BMI, hepatitis C, and caller-assigned Charlson groupings. CCI group is those weights (0/1/2/3+) times age band. The 0-100 score needs unpublished development min/max Xbeta; magent does not invent it. Paper prints score 30 to 1/3/8/18% and 45 to 6/14/35/61% at 1/2/5/10 years. Not a diagnosis or individual prognosis. magent does not code the chart.", "type": "http", "serviceName": "magent", "resourceType": "Agent Service", "accepts": [ { "scheme": "exact", "network": "eip155:8453", "payTo": "0x836Be278f1739fB4308091cD1852F7971Bc19Ee2", "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913", "amount": "5000", "amountUsd": 0.005, "maxTimeoutSeconds": 600 } ], "outputSchema": { "properties": { "example": { "type": "object" }, "type": { "type": "string" } }, "required": [ "type" ], "type": "object" }, "extensions": { "bazaar": { "info": { "iconUrl": "https://api.magentlab.com/favicon.ico", "input": { "body": { "items": [ { "age": 55, "albumin_g_dl": 4, "any_malignancy": false, "bmi_kg_m2": 25, "cerebrovascular_disease": false, "chronic_pulmonary_disease": false, "congestive_heart_failure": false, "dementia": false, "diabetes_with_complications": false, "diabetes_without_complications": false, "egfr_ml_min_1_73m2": 90, "fib4": 1, "hemiplegia_or_paraplegia": false, "hemoglobin_g_dl": 14, "hepatitis_c": false, "kidney_mild_to_moderate": false, "kidney_severe": false, "liver_mild": false, "liver_moderate_to_severe": false, "metastatic_solid_tumor": false, "myocardial_infarction": false, "peptic_ulcer_disease": false, "peripheral_vascular_disease": false, "rheumatic_disease": false, "sex": "male", "wbc_10e9_l": 4 }, { "age": 55, "albumin_g_dl": 4, "any_malignancy": false, "bmi_kg_m2": 25, "cerebrovascular_disease": false, "chronic_pulmonary_disease": false, "congestive_heart_failure": false, "dementia": false, "diabetes_with_complications": false, "diabetes_without_complications": false, "egfr_ml_min_1_73m2": 90, "fib4": 1, "hemiplegia_or_paraplegia": false, "hemoglobin_g_dl": 14, "hepatitis_c": false, "kidney_mild_to_moderate": false, "kidney_severe": false, "liver_mild": false, "liver_moderate_to_severe": false, "metastatic_solid_tumor": false, "myocardial_infarction": false, "peptic_ulcer_disease": false, "peripheral_vascular_disease": false, "rheumatic_disease": false, "sex": "male", "wbc_10e9_l": 4 } ] }, "method": "POST", "type": "http" }, "output": { "example": { "count": 2, "items": [ { "age": 55, "age_band": "50_64", "albumin_g_dl": 4, "any_malignancy": false, "bmi_kg_m2": 25, "cci_group": "0", "cci_score": 0, "cerebrovascular_disease": false, "chronic_pulmonary_disease": false, "citation": { "authors": "McGinnis KA, Justice AC, Marconi VC, et al.", "doi": "10.3389/fmed.2023.1342466", "id": "mcginnis-2024-vacs-cci", "pmid": "38356736", "source": "Front Med (Lausanne). 2024;10:1342466", "title": "Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration" }, "congestive_heart_failure": false, "dementia": false, "diabetes_with_complications": false, "diabetes_without_complications": false, "disclaimer": "Not a medical device. 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Deterministic published-formula or published-code output for autonomous agents. 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Deterministic published-formula or published-code output for autonomous agents. 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Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "egfr_ml_min_1_73m2": 90, "fib4": 1, "formula": "vacs_cci", "formula_expression": "lp = sex_female -0.513 + age_poly(X=age-50, 0.278/0.006/-0.001) + hb_poly(X=hemoglobin-14, -0.115/0.024/0.004) + fib4_poly(X, 0.205/-0.006) + egfr_poly(X=egfr-90, 0.071/0.036/0.002) + alb_poly(X=albumin-4, -0.405/0.326/0.156) + wbc_poly(X=WBC-4, -0.011/0.053/-0.008/0.000) + bmi_poly(X=BMI-25, -0.061/0.005/0.000) + hepatitis_c 0.273 + Table 2 Charlson condition coefficients + CCI-group x age-band interaction (CCI 0/1/2/3+ by <50, 50-64, 65-79, 80+; CCI 1 x 50-64 is reference 0); cci_group from caller-assigned condition weights (MI 1, CHF 1, PVD 1, CVD 1, dementia 1, pulmonary 1, rheumatic 1, PUD 1, DM without 1, DM with 2, hemiplegia 2, kidney mild-to-moderate 2, kidney severe 2, any malignancy 2, metastatic 6, liver mild 1, liver moderate-to-severe 3); McGinnis 2024 Table 2 Model 7; 1st/99th percentile winsorizing not published; 0-100 score uses unpublished development min/max Xbeta so magent does not scale; paper prints 0-100 score 30 → 1-year 1%, 2-year 3%, 5-year 8%, 10-year 18% and score 45 → 6%, 14%, 35%, 61%; no published S0; 2025 corrigendum PMID 39845833 does not change Table 2 coefficients; caller-assigned comorbidities, FIB-4, and eGFR", "hemiplegia_or_paraplegia": false, "hemoglobin_g_dl": 14, "hepatitis_c": false, "kidney_mild_to_moderate": false, "kidney_severe": false, "linear_predictor": 1.228, "liver_mild": false, "liver_moderate_to_severe": false, "metastatic_solid_tumor": false, "myocardial_infarction": false, "peptic_ulcer_disease": false, "peripheral_vascular_disease": false, "rheumatic_disease": false, "sex": "male", "wbc_10e9_l": 4 } ], "path": "/api/calc/vacs_cci" }, "type": "json" } }, "schema": { "$schema": "https://json-schema.org/draft/2020-12/schema", "properties": { "input": { "additionalProperties": false, "properties": { "body": { "additionalProperties": false, "properties": { "items": { "items": { "properties": { "age": { "description": "Age in years (integer 18-120). 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Table 2 centers at (BMI-25). magent does not compute BMI from height and weight.", "type": "number" }, "cerebrovascular_disease": { "description": "Caller-assigned cerebrovascular disease (McGinnis 2024 Table 2). true adds 0.114 to lp and 1 to the CCI grouping. magent does not diagnose stroke.", "type": "boolean" }, "chronic_pulmonary_disease": { "description": "Caller-assigned chronic pulmonary disease (McGinnis 2024 Table 2). true adds 0.279 to lp and 1 to the CCI grouping. magent does not diagnose lung disease.", "type": "boolean" }, "congestive_heart_failure": { "description": "Caller-assigned congestive heart failure (McGinnis 2024 Table 2). true adds 0.420 to lp and 1 to the CCI grouping. magent does not diagnose heart failure.", "type": "boolean" }, "dementia": { "description": "Caller-assigned dementia (McGinnis 2024 Table 2). true adds 0.489 to lp and 1 to the CCI grouping. magent does not diagnose dementia.", "type": "boolean" }, "diabetes_with_complications": { "description": "Caller-assigned diabetes with chronic complications (McGinnis 2024 Table 2). true adds 0.075 to lp and 2 to the CCI grouping. magent does not diagnose diabetes.", "type": "boolean" }, "diabetes_without_complications": { "description": "Caller-assigned diabetes without chronic complications (McGinnis 2024 Table 2). true adds 0.053 to lp and 1 to the CCI grouping. magent does not diagnose diabetes.", "type": "boolean" }, "egfr_ml_min_1_73m2": { "description": "Caller-assigned eGFR in mL/min/1.73m² (0-200). 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