Agent Service · x402 · early usage

Hegele 2025 NAFCS

by api.magentlab.com · discovered, not yet claimed by its owner · updated 2026-10-12

30d calls3

30d payers1

MethodPOST

Outputjson

Mirrored from Coinbase's public x402 Bazaar. The description is the provider's own text and has not been reviewed here; the payment requirements are copied as published.

What it does

Hegele 2025 NAFCS. Table 3 points from age or early HTG onset, BMI, abdominal pain or pancreatitis, secondary factors, fasting TG >880 mg/dL or >10 mmol/L, TG/TC >8 (mg/dL) or >3.5 (mmol/L), and apo B <1.0 g/L, plus published interactions. Max 100. ≥60 definite classical FCS; ≥45 very likely. Not a diagnosis or genetic test. Not Simon Broome or Dutch FH. magent does not examine the patient or assay lipids. Not a medical device.

Tags: nafcs · fcs · lipids · chylomicronemia · hegele-2025 · bazaar

Call contract

Method: POST
Input: HTTP request
Output: json
Last paid call: 2026-10-12

Input example from Bazaar metadata

{
  "items": [
    {
      "abdominal_history": "none",
      "age_years": 40,
      "apo_b_g_l": 1.2,
      "apo_b_mg_dl": 120,
      "bmi_below_threshold": false,
      "htg_onset_before_age_10": false,
      "secondary_factors_present": true,
      "tg_mg_dl": 500,
      "tg_mmol_l": 8,
      "tg_tc_ratio_mg_dl": 5,
      "tg_tc_ratio_mmol_l": 2
    },
    {
      "abdominal_history": "none",
      "age_years": 40,
      "apo_b_g_l": 1.2,
      "apo_b_mg_dl": 120,
      "bmi_below_threshold": false,
      "htg_onset_before_age_10": false,
      "secondary_factors_present": true,
      "tg_mg_dl": 500,
      "tg_mmol_l": 8,
      "tg_tc_ratio_mg_dl": 5,
      "tg_tc_ratio_mmol_l": 2
    }
  ]
}

Output example

{
  "count": 2,
  "items": [
    {
      "age_years": 40,
      "all_tg_severely_elevated": false,
      "citation": {
        "authors": "Hegele RA, Ahmad Z, Ashraf A, et al.",
        "doi": "10.1016/j.jacl.2024.09.008",
        "id": "hegele-2025",
        "pmid": "39537503",
        "source": "J Clin Lipidol. 2025;19(1):83-94",
        "title": "Development and validation of clinical criteria to identify familial chylomicronemia syndrome (FCS) in North America"
      },
      "components": [
        {
          "factor": "early_htg_onset",
          "points": 0,
          "present": false
        },
        {
          "factor": "child_htg",
          "points": 0,
          "present": false
        },
        {
          "factor": "all_tg_severely_elevated",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_tg_tc_ratio",
          "points": 0,
          "present": false
        },
        {
          "factor": "low_apo_b",
          "points": 0,
          "present": false
        },
        {
          "factor": "bmi_below_threshold",
          "points": 0,
          "present": false
        },
        {
          "factor": "abdominal_pain",
          "points": 0,
          "present": false
        },
        {
          "factor": "pancreatitis",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_secondary_factors",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_ratio_and_low_apo_b",
          "points": 0,
          "present": false
        },
        {
          "factor": "child_and_no_secondary",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_ratio_and_no_secondary",
          "points": 0,
          "present": false
        }
      ],
      "definite_classical_fcs": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "nafcs",
      "formula_expression": "NAFCS = early_htg_onset 12 (age_years ≥10 and htg_onset_before_age_10) + child_htg 12 (age_years 1-9) + all_tg_severely_elevated 13 (all fasting TG >880 mg/dL or >10 mmol/L) + high_tg_tc_ratio 8 (TG/TC >8 mg/dL or >3.5 mmol/L) + low_apo_b 12 (apo B <1.0 g/L or <100 mg/dL) + bmi_below_threshold 9 (BMI <25 kg/m2 or <85th percentile) + abdominal_pain 9 (recurrent abdominal pain without pancreatitis) + pancreatitis 16 + no_secondary_factors 11 + high_ratio_and_low_apo_b 7 + child_and_no_secondary 7 + high_ratio_and_no_secondary 5 (Hegele 2025 Table 3, parameter estimates ×10); max 100; ≥60 definite classical FCS; ≥45 very likely classical FCS",
      "high_tg_tc_ratio": false,
      "low_apo_b": false,
      "max_score": 100,
      "score": 0,
      "very_likely_classical_fcs": false
    },
    {
      "age_years": 40,
      "all_tg_severely_elevated": false,
      "citation": {
        "authors": "Hegele RA, Ahmad Z, Ashraf A, et al.",
        "doi": "10.1016/j.jacl.2024.09.008",
        "id": "hegele-2025",
        "pmid": "39537503",
        "source": "J Clin Lipidol. 2025;19(1):83-94",
        "title": "Development and validation of clinical criteria to identify familial chylomicronemia syndrome (FCS) in North America"
      },
      "components": [
        {
          "factor": "early_htg_onset",
          "points": 0,
          "present": false
        },
        {
          "factor": "child_htg",
          "points": 0,
          "present": false
        },
        {
          "factor": "all_tg_severely_elevated",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_tg_tc_ratio",
          "points": 0,
          "present": false
        },
        {
          "factor": "low_apo_b",
          "points": 0,
          "present": false
        },
        {
          "factor": "bmi_below_threshold",
          "points": 0,
          "present": false
        },
        {
          "factor": "abdominal_pain",
          "points": 0,
          "present": false
        },
        {
          "factor": "pancreatitis",
          "points": 0,
          "present": false
        },
        {
          "factor": "no_secondary_factors",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_ratio_and_low_apo_b",
          "points": 0,
          "present": false
        },
        {
          "factor": "child_and_no_secondary",
          "points": 0,
          "present": false
        },
        {
          "factor": "high_ratio_and_no_secondary",
          "points": 0,
          "present": false
        }
      ],
      "definite_classical_fcs": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "nafcs",
      "formula_expression": "NAFCS = early_htg_onset 12 (age_years ≥10 and htg_onset_before_age_10) + child_htg 12 (age_years 1-9) + all_tg_severely_elevated 13 (all fasting TG >880 mg/dL or >10 mmol/L) + high_tg_tc_ratio 8 (TG/TC >8 mg/dL or >3.5 mmol/L) + low_apo_b 12 (apo B <1.0 g/L or <100 mg/dL) + bmi_below_threshold 9 (BMI <25 kg/m2 or <85th percentile) + abdominal_pain 9 (recurrent abdominal pain without pancreatitis) + pancreatitis 16 + no_secondary_factors 11 + high_ratio_and_low_apo_b 7 + child_and_no_secondary 7 + high_ratio_and_no_secondary 5 (Hegele 2025 Table 3, parameter estimates ×10); max 100; ≥60 definite classical FCS; ≥45 very likely classical FCS",
      "high_tg_tc_ratio": false,
      "low_apo_b": false,
      "max_score": 100,
      "score": 0,
      "very_likely_classical_fcs": false
    }
  ],
  "path": "/api/calc/nafcs"
}

Use with an agent

Discover. Agents find this listing with GET https://bazaar.saylorinnovations.com/discovery/search?query=…, the MCP tool search_resources, or /discovery/resources.
Inspect. Fetch /resources/39547.json for the price and payment options.
Pay. Call GET https://api.magentlab.com/api/calc/nafcs. The provider answers 402 with its payment requirements. An x402 client signs one of the options below and retries with PAYMENT-SIGNATURE.
Execute. The provider returns 200 with the data. Agent Bazaar is not in the request path and never sees your payment.

For humans

You don't need an account or an API key; you need a wallet holding a small amount of USDC on Base, and an x402-capable client (see the examples below). Call the endpoint unpaid first to see exactly what it asks for.

Pricing & payment

Price: $0.005 / request
Protocol: x402 v2
Auth: No account or API key. Pay per request.
Networks: Base
Demand: 3 calls · 1 unique payers in 30d (public x402 Bazaar data)

x402 payment requirements

Scheme	Network	Asset	Amount	Pay to	Timeout
exact	Base eip155:8453	USDC	$0.005	0x836Be278f1739fB4308091cD1852F7971Bc19Ee2	600s

accepts[] (raw JSON)

[
  {
    "scheme": "exact",
    "network": "eip155:8453",
    "payTo": "0x836Be278f1739fB4308091cD1852F7971Bc19Ee2",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "5000",
    "amountUsd": 0.005,
    "maxTimeoutSeconds": 600
  }
]

Schemas

Output schema (JSON Schema)

{
  "properties": {
    "example": {
      "type": "object"
    },
    "type": {
      "type": "string"
    }
  },
  "required": [
    "type"
  ],
  "type": "object"
}

Example shape — generated from the schema, not a captured live response

{
  "example": {},
  "type": "string"
}

Examples

curl

curl "https://api.magentlab.com/api/calc/nafcs"
# -> 402 Payment Required, accepts[] lists how to pay
# retry with a PAYMENT-SIGNATURE (or PAYMENT header) once paid

JavaScript

const res = await fetch("https://api.magentlab.com/api/calc/nafcs");
if (res.status === 402) {
  const { accepts } = await res.json();
  // pay one of accepts[] via an x402 client, then retry with the payment header
}

Python

import httpx
res = httpx.get("https://api.magentlab.com/api/calc/nafcs")
if res.status_code == 402:
    accepts = res.json()["accepts"]
    # pay one of accepts[] via an x402 client, then retry with the payment header

Details

Provider: api.magentlab.com
Endpoint: https://api.magentlab.com/api/calc/nafcs
Machine-readable: /resources/39547.json